Heterotrimeric G-protein GTPase

This group comprises GTP-hydrolyzing systems, where GTP and GDP alternate in binding.

Source:http://purl.uniprot.org/enzyme/3.6.5.1

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At least 16 different alpha subunits (39-52 kDa), 5 beta subunits (36 kDa) and 12 gamma subunits (6-9 kDa) are known., G(olf) is instrumental in odor perception, transducin in vision and gustducin in taste recognition., This group comprises GTP-hydrolyzing systems, where GTP and GDP alternate in binding., This group includes stimulatory and inhibitory G-proteins such as G(s), G(i), G(o) and G(olf), targeting adenylate cyclase and/or K(+) and Ca(2+) channels; G(q) stimulating phospholipase C; transducin activating cGMP phosphodiesterase; gustducin activating cAMP phosphodiesterase.
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Heterotrimeric G-protein GTPase
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GTP + H(2)O = GDP + phosphate.