In addition (R)-piperidine-3-carboxamide is hydrolyzed to (R)-piperidine-3-carboxylic acid and NH(3), and (R)-N-tert-butylpiperazine-2-carboxamide is hydrolyzed to (R)-piperazine-2-carboxylic acid and tert-butylamine with lower activity.
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rdfs:comment |
In addition (R)-piperidine-3-carboxamide is hydrolyzed to (R)-piperidine-3-carboxylic acid and NH(3), and (R)-N-tert-butylpiperazine-2-carboxamide is hydrolyzed to (R)-piperazine-2-carboxylic acid and tert-butylamine with lower activity.,
The enzyme does not act on the other amide substrates which are hydrolyzed by EC 3.5.1.4 (amidase).
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uniprot:name |
(R)-amidase,
R-amidase,
R-stereospecific amidase
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uniprot:activity |
(1) (R)-piperazine-2-carboxamide + H(2)O = (R)-piperazine-2-carboxylic acid + NH(3).,
(2) Beta-alaninamide + H(2)O = beta-alanine + NH(3).
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