BACE2

Belongs to peptidase family A1.

Source:http://purl.uniprot.org/enzyme/3.4.23.45

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Named Graph Language Inference

Statements in which the resource exists as a subject.
Predicate	Object
rdf:type	uniprot:Enzyme
rdfs:comment	Belongs to peptidase family A1., Can cleave beta-amyloid precursor protein to form the amyloidogenic beta-peptide that is implicated in the pathology of Alzheimer's disease, but is not significantly expressed in human brain.
rdfs:subClassOf	http://purl.uniprot.org/enzyme/3.4.23.-
skos:broaderTransitive	http://purl.uniprot.org/enzyme/3.4.23.-
uniprot:name	ASP1, BACE2, Beta-secretase, Beta-site APP-cleaving enzyme 2, Beta-site Alzheimer's amyloid precursor protein cleaving enzyme 2, Down region aspartic protease, Memapsin 1, Membrane-associated aspartic protease 1
uniprot:activity	Broad endopeptidase specificity. Cleaves Glu-Val-Asn-Leu-\|-Asp-Ala-Glu-Phe in the Swedish variant of Alzheimer's amyloid precursor protein.