Pepsin A

Belongs to peptidase family A1.

Source:http://purl.uniprot.org/enzyme/3.4.23.1

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Named Graph Language Inference

Statements in which the resource exists as a subject.
Predicate	Object
rdf:type	uniprot:Enzyme
rdfs:comment	Belongs to peptidase family A1., The predominant endopeptidase in the gastric juice of vertebrates, formed from pepsinogen A by limited proteolysis.
rdfs:subClassOf	http://purl.uniprot.org/enzyme/3.4.23.-
skos:broaderTransitive	http://purl.uniprot.org/enzyme/3.4.23.-
uniprot:name	Pepsin, Pepsin A
uniprot:replaces	http://purl.uniprot.org/enzyme/3.4.4.1
uniprot:activity	Preferential cleavage: hydrophobic, preferably aromatic, residues in P1 and P1' positions. Cleaves 1-Phe-\|-Val-2, 4-Gln-\|-His-5, 13-Glu-\|-Ala-14, 14-Ala-\|-Leu-15, 15-Leu-\|-Tyr-16, 16-Tyr-\|-Leu-17, 23-Gly-\|-Phe-24, 24-Phe-\|-Phe-25 and 25-Phe-\|-Tyr-26 bonds in the B chain of insulin.