The enzyme catalyzes the liberation of Gal-(1->3)-beta-GalNAc alpha-linked to serine or threonine residues of mucin-type glycoproteins.
| Predicate | Object |
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| rdf:type | |
| rdfs:comment |
EngBF from Bifidobacterium longum specifically acts on core 1-type O-glycan to release the disaccharide Gal-(1->3)-beta-GalNAc.,
The enzyme catalyzes the liberation of Gal-(1->3)-beta-GalNAc alpha-linked to serine or threonine residues of mucin-type glycoproteins.,
The enzyme may play an important role in the degradation and utilization of mucins having core 1 O-glycan.,
The enzymes from Clostridium perfringens, Enterococcus faecalis, Propionibacterium acnes and Alcaligenes faecalis show broader specificity (e.g. release of the core 2 trisaccharide Gal-(1->3)-beta-(GlcNAc-(1->6)-beta)-GalNAc or the core 3 disaccharide GlcNAc-(1->3)-beta-GalNAc).
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| rdfs:subClassOf | |
| skos:broaderTransitive | |
| uniprot:name |
D-galactosyl-3-(N-acetyl-alpha-D-galactosaminyl)-L-serine mucinaminohydrolase,
D-galactosyl-N-acetyl-alpha-D-galactosamine D-galactosyl-N-acetyl-galactosaminohydrolase,
Endo-alpha-GalNAc-ase,
Endo-alpha-N-acetyl-D-galactosaminidase,
Endo-alpha-N-acetylgalactosaminidase,
Endo-alpha-acetylgalactosaminidase,
Glycopeptide alpha-N-acetylgalactosaminidase,
Mucinaminylserine mucinaminidase
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| uniprot:replaces | |
| uniprot:activity |
3-O-beta-D-galactosyl-N-acetyl-alpha-D-galactosaminyl-L-serine-[protein] + H(2)O = 3-O-beta-D-galactosyl-N-acetyl-alpha-D-galactosamine + L-serine-[protein].
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