This enzyme catalyzes the Mg(2+)-dependent dephosphorylation of a 1,2-diacylglycerol-3-phosphate, yielding a 1,2-diacyl-sn-glycerol (DAG), the substrate for de novo lipid synthesis via the Kennedy pathway and for the synthesis of triacylglycerol.
| Predicate | Object |
|---|---|
| rdf:type | |
| rdfs:comment |
In lipid signaling, the enzyme generates a pool of DAG to be used for protein kinase C activation.,
The mammalian enzymes are known as lipins.,
This enzyme catalyzes the Mg(2+)-dependent dephosphorylation of a 1,2-diacylglycerol-3-phosphate, yielding a 1,2-diacyl-sn-glycerol (DAG), the substrate for de novo lipid synthesis via the Kennedy pathway and for the synthesis of triacylglycerol.
|
| rdfs:subClassOf | |
| skos:broaderTransitive | |
| uniprot:name |
Lipin,
Phosphatic acid phosphatase,
Phosphatic acid phosphohydrolase,
Phosphatidate phosphatase,
Phosphatidic acid phospphatase
|
| uniprot:activity |
A 1,2-diacylglycerol 3-phosphate + H(2)O = a 1,2-diacyl-sn-glycerol + phosphate.
|
| uniprot:cofactor |
Magnesium
|