An endoribonuclease that cleaves double-stranded RNA molecules.
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| rdf:type | |
| rdfs:comment |
An endoribonuclease that cleaves double-stranded RNA molecules.,
RNase III is involved in both rRNA processing and mRNA processing and decay.,
Specificity is conferred by negative determinants, i.e., the presence of certain Watson-Crick base-pairs at specific positions that strongly inhibit cleavage.,
The cleavage can be either a single-stranded nick or double-stranded break in the RNA, depending in part upon the degree of base-pairing in the region of the cleavage site.
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| rdfs:subClassOf | |
| skos:broaderTransitive | |
| uniprot:name |
RNase III,
Ribonuclease 3,
Ribonuclease III
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| uniprot:activity |
Endonucleolytic cleavage to 5'-phosphomonoester.
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