The transforming growth factor beta (TGF-beta) family of cytokines regulates cell proliferation, differentiation, recognition and death.
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| rdf:type | |
| rdfs:comment |
Bound TGF-beta is then recognized by receptor I, which is phosphorylated and can propagate the signal to downstream substrates.,
Signaling occurs by the binding of ligand to the type II receptor, which is the constitutively active kinase.,
The transforming growth factor beta (TGF-beta) family of cytokines regulates cell proliferation, differentiation, recognition and death.
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| rdfs:subClassOf | |
| skos:broaderTransitive | |
| uniprot:name |
Activin receptor kinase,
Receptor protein serine/threonine kinase,
Receptor serine/threonine protein kinase,
Receptor type I serine/threonine protein kinase,
Receptor type II serine/threonine protein kinase,
TGF-beta kinase
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| uniprot:replaces | |
| uniprot:activity |
ATP + [receptor-protein] = ADP + [receptor-protein] phosphate.
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