cGMP is required to activate this enzyme.
| Predicate | Object |
|---|---|
| rdf:type | |
| rdfs:comment |
Binding of cGMP causes a conformational change that is associated with activation of the kinase.,
The C-terminal region of each polypeptide chain contains the catalytic domain that includes the ATP and protein substrate binding sites.,
The enzyme also has two allosteric cGMP-binding sites (sites A and B).,
The enzyme occurs as a dimer in higher eukaryotes.,
This domain catalyzes the phosphorylation by ATP to specific serine or threonine residues in protein substrates.,
cGMP is required to activate this enzyme.
|
| rdfs:subClassOf | |
| skos:broaderTransitive | |
| uniprot:name |
3':5'-cyclic GMP-dependent protein kinase,
Guanosine 3':5'-cyclic monophosphate-dependent protein kinase,
PKG,
PKG 1-alpha,
PKG 1-beta,
PKG II,
cGMP-dependent protein kinase,
cGMP-dependent protein kinase I-beta
|
| uniprot:replaces | |
| uniprot:activity |
ATP + a protein = ADP + a phosphoprotein.
|