The ADP-D-ribosyl group of NAD(+) is transferred to an acceptor carboxy group on a histone or the enzyme itself, and further ADP-ribosyl groups are transferred to the 2'-position of the terminal adenosine moiety, building up a polymer with an average chain length of 20-30 units.
| Predicate | Object |
|---|---|
| rdf:type | |
| rdfs:comment |
The ADP-D-ribosyl group of NAD(+) is transferred to an acceptor carboxy group on a histone or the enzyme itself, and further ADP-ribosyl groups are transferred to the 2'-position of the terminal adenosine moiety, building up a polymer with an average chain length of 20-30 units.
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| rdfs:subClassOf | |
| skos:broaderTransitive | |
| uniprot:name |
ADP-ribosyltransferase (polymerizing),
NAD(+) ADP-ribosyltransferase,
Poly(ADP-ribose) synthetase,
Poly(ADP-ribose)polymerase,
Poly(adenosine diphosphate ribose) polymerase
|
| uniprot:activity |
NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.
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