O-linked N-acetylglucosaminyltransferase

Within higher eukaryotes post-translational modification of protein serines/threonines with N-acetylglucosamine (O-GlcNAc) is dynamic, inducible and abundant, regulating many cellular processes by interfering with protein phosphorylation.

Source:http://purl.uniprot.org/enzyme/2.4.1.255

Download in:

Named Graph Language Inference

Statements in which the resource exists as a subject.
Predicate	Object
rdf:type	uniprot:Enzyme
rdfs:comment	EC 2.4.1.255 transfers GlcNAc onto substrate proteins and EC 3.2.1.169 cleaves GlcNAc from the modified proteins., Within higher eukaryotes post-translational modification of protein serines/threonines with N-acetylglucosamine (O-GlcNAc) is dynamic, inducible and abundant, regulating many cellular processes by interfering with protein phosphorylation.
rdfs:subClassOf	http://purl.uniprot.org/enzyme/2.4.1.-
skos:broaderTransitive	http://purl.uniprot.org/enzyme/2.4.1.-
uniprot:name	O-linked N-acetylglucosaminyltransferase, OGTase, Protein O-GlcNAc transferase
uniprot:activity	(1) UDP-N-acetyl-D-glucosamine + [protein]-L-serine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine., (2) UDP-N-acetyl-D-glucosamine + [protein]-L-threonine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine.