N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase

Involved in the biosynthesis of chondroitin and dermatan sulfate.

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Predicate	Object
rdf:type	uniprot:Enzyme
rdfs:comment	Involved in the biosynthesis of chondroitin and dermatan sulfate., Similar chondroitin synthase 'copolymerases' can be found in Pasteurella multocida and Escherichia coli., The human chondroitin synthetase is a bifunctional glycosyltransferase, which also has the EC 2.4.1.175 activity required for the synthesis of the chondroitin sulfate disaccharide repeats., There is also another human protein with apparently only the 3-beta-glucuronosyltransferase activity.
rdfs:subClassOf	http://purl.uniprot.org/enzyme/2.4.1.-
skos:broaderTransitive	http://purl.uniprot.org/enzyme/2.4.1.-
uniprot:name	Chondroitin glucuronyltransferase II, N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase
uniprot:activity	UDP-alpha-D-glucuronate + N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan = UDP + beta-D-glucuronosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan.