The enzyme acetylates the wobble base C34 of the CAU anticodon of elongation-specific tRNA(Met).
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rdfs:comment |
Escherichia coli TmcA strictly discriminates elongator tRNA(Met) from tRNA(Ile), which is structurally similar and has the same anticodon loop, mainly by recognizing the C27-G43 pair in the anticodon stem.,
The enzyme acetylates the wobble base C34 of the CAU anticodon of elongation-specific tRNA(Met).,
The enzyme can use GTP in place of ATP for formation of N(4)-acetylcytidine.
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uniprot:name |
tRNA(Met) cytidine acetyltransferase
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uniprot:activity |
(Elongator tRNA(Met))-cytidine(34) + ATP + acetyl-CoA = (elongator tRNA(Met))-N(4)-acetylcytidine(34) + ADP + phosphate + CoA.
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