Involved in the biosynthesis of vitamin K(2) (menaquinone).
| Predicate | Object |
|---|---|
| rdf:type | |
| rdfs:comment |
In most anaerobes and all Gram-positive aerobes, menaquinone is the sole electron transporter in the respiratory chain and is essential for their survival.,
Involved in the biosynthesis of vitamin K(2) (menaquinone).,
It had previously been thought that the products of the reaction were (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate (SHCHC), pyruvate and CO(2) but it is now known that two separate enzymes are involved: this enzyme and EC 4.2.99.20.,
Under basic conditions, the product can spontaneously lose pyruvate to form SHCHC.
|
| rdfs:subClassOf | |
| skos:broaderTransitive | |
| uniprot:name |
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase,
SEPHCHC synthase
|
| uniprot:replaces | |
| uniprot:activity |
Isochorismate + 2-oxoglutarate = 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO(2).
|
| uniprot:cofactor |
Magnesium
|