23S rRNA (adenine(2503)-C(2))-methyltransferase

This enzyme is a member of the 'AdoMet radical' (radical SAM) family.

Source:http://purl.uniprot.org/enzyme/2.1.1.192

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
rdfs:comment
Cf. EC 2.1.1.224., It will also methylate 8-methyladenosine(2503) of 23S rRNA., RlmN is an endogenous enzyme used by the cell to refine functions of the ribosome in protein synthesis., S-adenosyl-L-methionine acts as both a radical generator and as the source of the appended methyl group., The enzyme methylates adenosine by a radical mechanism with CH(2) from the S-adenosyl-L-methionine and retention of the hydrogen at C-2 of adenosine(2503) of 23S rRNA., This enzyme is a member of the 'AdoMet radical' (radical SAM) family.
rdfs:subClassOf
skos:broaderTransitive
uniprot:name
23S rRNA (adenine(2503)-C(2))-methyltransferase
uniprot:activity
2 S-adenosyl-L-methionine + adenine(2503) in 23S rRNA = S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + 2-methyladenine(2503) in 23S rRNA.
uniprot:cofactor
Iron-sulfur