KsgA introduces the most highly conserved ribosomal RNA modification, the dimethylation of adenine(1518) and adenine(1519) in 16S rRNA.
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rdfs:comment |
KsgA introduces the most highly conserved ribosomal RNA modification, the dimethylation of adenine(1518) and adenine(1519) in 16S rRNA.,
Strains lacking the methylase are resistant to kasugamycin.
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uniprot:name |
16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase
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uniprot:activity |
4 S-adenosyl-L-methionine + adenine(1518)/adenine(1519) in 16S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1518)/N(6)-dimethyladenine(1519) in 16S rRNA.
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