The reaction occurs in the reverse direction to that shown above.
| Predicate | Object |
|---|---|
| rdf:type | |
| rdfs:comment |
Exhibits high specificity for the reduction of the S-form of L-methionine S-oxide, acting faster on the residue in a peptide than on the free amino acid.,
On the free amino acid, it can also reduce D-methionine (S)-S-oxide but more slowly.,
Plays a role in preventing oxidative-stress damage caused by reactive oxygen species by reducing the oxidized form of methionine back to methionine and thereby reactivating peptides that had been damaged.,
The reaction occurs in the reverse direction to that shown above.,
The reaction proceeds via a sulfenic-acid intermediate.
|
| rdfs:subClassOf | |
| skos:broaderTransitive | |
| uniprot:name |
Methionine S-oxide reductase,
Methionine S-oxide reductase (S-form oxidizing),
Methionine sulfoxide reductase,
Methionine sulfoxide reductase A,
Methionine sulphoxide reductase A,
Peptide Met(O) reductase,
Peptide methionine sulfoxide reductase,
Peptide-methionine (S)-S-oxide reductase
|
| uniprot:replaces | |
| uniprot:activity |
(1) Peptide-L-methionine + thioredoxin disulfide + H(2)O = peptide-L-methionine (S)-S-oxide + thioredoxin.,
(2) L-methionine + thioredoxin disulfide + H(2)O = L-methionine (S)-S-oxide + thioredoxin.
|