Long-chain-acyl-CoA dehydrogenase

One of several enzymes that catalyze the first step in fatty acids beta-oxidation.

Source:http://purl.uniprot.org/enzyme/1.3.8.8

Statements in which the resource exists as a subject.
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It is most active with C(14) and C(16), and has no activity with C(4), C(6) or C(24)., One of several enzymes that catalyze the first step in fatty acids beta-oxidation., The enzyme from pig liver can accept substrates with acyl chain lengths of 6 to at least 16 carbon atoms., The enzyme from rat can accept substrates with C(8)-C(22)., The highest activity was found with C(12), and the rates with C(8) and C(16) were 80% and 70%, respectively., cf. EC 1.3.8.1, EC 1.3.8.8 and EC 1.3.8.9.
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Long-chain-acyl-CoA dehydrogenase
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Long-chain-acyl-CoA + electron-transfer flavoprotein = long-chain-2,3-dehydroacyl-CoA + reduced electron-transfer flavoprotein.
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FAD