The membrane bound class 2 dihydroorotate dehydrogenase (EC 1.3.5.2) uses quinone as electron acceptor.
| Predicate | Object |
|---|---|
| rdf:type | |
| rdfs:comment |
Other class 1 dihydroorotate dehydrogenases use either fumarate (EC 1.3.98.1) or NADP(+) (EC 1.3.1.15) as electron acceptor.,
The enzyme consists of two subunits, an FMN binding catalytic subunit and a FAD and iron-sulfur binding electron transfer subunit.,
The membrane bound class 2 dihydroorotate dehydrogenase (EC 1.3.5.2) uses quinone as electron acceptor.,
The reaction, which takes place in the cytosol, is the only redox reaction in the de-novo biosynthesis of pyrimidine nucleotides.
|
| rdfs:subClassOf | |
| skos:broaderTransitive | |
| uniprot:name |
DHOD,
DHODase,
DHOdehase,
Dihydroorotate dehydrogenase (NAD(+)),
Dihydroorotate oxidase,
Orotate reductase (NADH(2)),
Orotate reductase (NADH)
|
| uniprot:activity |
(S)-dihydroorotate + NAD(+) = orotate + NADH.
|
| uniprot:cofactor |
FAD,
FMN,
Iron-sulfur
|