The enzyme is capable of acting on a variety of nicotinate analogs to varying degrees, including pyrazine-2-carboxylate, pyrazine 2,3-dicarboxylate, trigonelline and 6-methylnicotinate.
| Predicate | Object |
|---|---|
| rdf:type | |
| rdfs:comment |
Forms part of the nicotinate-fermentation catabolism pathway in Eubacterium barkeri.,
Other enzymes involved in this pathway are EC 1.3.7.1, EC 3.5.2.18, EC 1.1.1.291, EC 5.4.99.4, EC 5.3.3.6, EC 4.2.1.85 and EC 4.1.3.32.,
The enzyme from Clostridium barkeri also possesses a catalytically essential, labile selenium that can be removed by reaction with cyanide.,
The enzyme is capable of acting on a variety of nicotinate analogs to varying degrees, including pyrazine-2-carboxylate, pyrazine 2,3-dicarboxylate, trigonelline and 6-methylnicotinate.
|
| rdfs:subClassOf | |
| skos:broaderTransitive | |
| uniprot:name |
Nicotinate dehydrogenase,
Nicotinate hydroxylase,
Nicotinic acid hydroxylase
|
| uniprot:replaces | |
| uniprot:activity |
Nicotinate + H(2)O + NADP(+) = 6-hydroxynicotinate + NADPH.
|
| uniprot:cofactor |
Flavoprotein,
Iron
|