The enzyme (P450) catalyzes successive hydroxylations of the 14-alpha-methyl group and C-15, followed by elimination as formate leaving the 14(15) double bond.
| Predicate | Object |
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| rdf:type | |
| rdfs:comment |
The enzyme (P450) catalyzes successive hydroxylations of the 14-alpha-methyl group and C-15, followed by elimination as formate leaving the 14(15) double bond.,
This enzyme acts on a range of steroids with a 14-alpha-methyl group.
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| rdfs:subClassOf | |
| skos:broaderTransitive | |
| uniprot:name |
Cytochrome P450 51,
Lanosterol 14-alpha-demethylase,
Lanosterol 14-demethylase,
Obtusufoliol 14-demethylase,
Sterol 14-alpha-demethylase,
Sterol 14-demethylase
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| uniprot:activity |
Obtusifoliol + 3 O(2) + 3 NADPH = 4-alpha-methyl-5-alpha-ergosta-8,14,24(28)-trien-3-beta-ol + formate + 3 NADP(+) + 4 H(2)O.
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| uniprot:cofactor |
Heme-thiolate
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