Catalyzes, together with EC 1.13.11.52, the first and rate-limiting step in the kynurenine pathway, the major pathway of tryptophan metabolism.
| Predicate | Object |
|---|---|
| rdf:type | |
| rdfs:comment |
Catalyzes, together with EC 1.13.11.52, the first and rate-limiting step in the kynurenine pathway, the major pathway of tryptophan metabolism.,
Specific for tryptophan as substrate, but is far more active with L-tryptophan than with D-tryptophan.
|
| rdfs:subClassOf | |
| skos:broaderTransitive | |
| uniprot:name |
Indolamine 2,3-dioxygenase,
Indoleamine 2,3-dioxygenase,
L-tryptophan 2,3-dioxygenase,
L-tryptophan pyrrolase,
Tryptamin 2,3-dioxygenase,
Tryptamine 2,3-dioxygenase,
Tryptophan 2,3-dioxygenase,
Tryptophan oxygenase,
Tryptophan peroxidase,
Tryptophan pyrrolase,
Tryptophanase
|
| uniprot:replaces | |
| uniprot:activity |
L-tryptophan + O(2) = N-formyl-L-kynurenine.
|
| uniprot:cofactor |
Heme
|