The second component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA (and modified forms thereof) to very-long-chain acyl CoAs.
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| rdf:type | |
| rdfs:comment |
Cf. EC 2.3.1.199, EC 4.2.1.134 and EC 1.3.1.93.,
The enzyme is active with substrates with chain length of C(16) to C(34), depending on the species.,
The second component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA (and modified forms thereof) to very-long-chain acyl CoAs.
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| rdfs:subClassOf | |
| skos:broaderTransitive | |
| uniprot:name |
Very-long-chain 3-ketoacyl-CoA reductase,
Very-long-chain 3-oxoacyl-CoA reductase,
Very-long-chain beta-ketoacyl-CoA reductase
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| uniprot:replaces | |
| uniprot:activity |
A very-long-chain (3R)-3-hydroxyacyl-CoA + NADP(+) = a very-long-chain 3-oxoacyl-CoA + NADPH.
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