We used RT-PCR to detect the expression in mouse molar and incisor tooth germs of 14 of the 19 known members of the Sox family of HMG box-containing transcription factors. These sequences fell into all 6 of the main subdivisions of the Sox family. In general, the relative transcript abundance of the different Sox genes is similar between molar and incisor tooth germs, although 3 low-abundance transcripts were found in only a single tooth type. The expression of Sox genes during tooth development has not been reported previously and further experiments will be required to determine their role in this process.
| Predicate | Object |
|---|---|
| rdf:type | |
| rdfs:comment |
We used RT-PCR to detect the expression in mouse molar and incisor tooth germs of 14 of the 19 known members of the Sox family of HMG box-containing transcription factors. These sequences fell into all 6 of the main subdivisions of the Sox family. In general, the relative transcript abundance of the different Sox genes is similar between molar and incisor tooth germs, although 3 low-abundance transcripts were found in only a single tooth type. The expression of Sox genes during tooth development has not been reported previously and further experiments will be required to determine their role in this process.
|
| skos:exactMatch | |
| uniprot:name |
Genomics
|
| uniprot:author |
Buchanan A.V.,
Stock D.W.,
Weiss K.M.,
Zhao Z.
|
| uniprot:date |
1996
|
| uniprot:pages |
234-237
|
| uniprot:title |
Numerous members of the Sox family of HMG box-containing genes are expressed in developing mouse teeth.
|
| uniprot:volume |
37
|
| dc-term:identifier |
doi:10.1006/geno.1996.0548
|