A cDNA encoding rat H(+)-coupled peptide transporter PEPT2 was isolated. The cDNA encoded a protein of 729 amino acids with 48% amino acid identity to the rat PEPT1. The mRNA expression of rat PEPT2 was predominant in the kidney. When expressed in Xenopus oocytes, rat PEPT2 stimulated the uptake of bestatin, a dipeptide-like drug.
| Predicate | Object |
|---|---|
| rdf:type | |
| rdfs:comment |
A cDNA encoding rat H(+)-coupled peptide transporter PEPT2 was isolated. The cDNA encoded a protein of 729 amino acids with 48% amino acid identity to the rat PEPT1. The mRNA expression of rat PEPT2 was predominant in the kidney. When expressed in Xenopus oocytes, rat PEPT2 stimulated the uptake of bestatin, a dipeptide-like drug.
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| skos:exactMatch | |
| uniprot:name |
Biochim. Biophys. Acta
|
| uniprot:author |
Inui K.,
Okuda M.,
Saito H.,
Sasaki S.,
Terada T.
|
| uniprot:date |
1996
|
| uniprot:pages |
173-177
|
| uniprot:title |
Molecular cloning and tissue distribution of rat peptide transporter PEPT2.
|
| uniprot:volume |
1280
|
| dc-term:identifier |
doi:10.1016/0005-2736(96)00024-7
|