A field isolate of Sendai virus, the Hamamatsu strain, was far more virulent in mice than the prototype Z strain. The Hamamatsu strain replicated more efficiently in the mouse lung than the Z strain, causing deteriorating lung lesions. Nucleotide sequence analysis of the HN, F and M genes revealed that the Hamamatsu strain was divergent from the prototype Z, Harris and Fushimi strains.
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rdfs:comment |
A field isolate of Sendai virus, the Hamamatsu strain, was far more virulent in mice than the prototype Z strain. The Hamamatsu strain replicated more efficiently in the mouse lung than the Z strain, causing deteriorating lung lesions. Nucleotide sequence analysis of the HN, F and M genes revealed that the Hamamatsu strain was divergent from the prototype Z, Harris and Fushimi strains.
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skos:exactMatch | |
uniprot:name |
Arch. Virol.
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uniprot:author |
Fujii Y.,
Kiyotani K.,
Sakaguchi T.,
Sasaki M.,
Yoshida T.
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uniprot:date |
1994
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uniprot:pages |
159-164
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uniprot:title |
A field isolate of Sendai virus: its high virulence to mice and genetic divergence from prototype strains.
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uniprot:volume |
135
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dc-term:identifier |
doi:10.1007/BF01309773
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