A major acute phase protein (pig-MAP) has been isolated from the sera of pigs after turpentine injection. The protein is the pig counterpart of a recently cloned human serum protein denominated PK-120, which is a putative substrate for kallikrein [Nishimura et al., 1995 FEBS Lett. 357, 207-211]. The protein exists in other mammalian species and it is also an acute phase protein, at least in the rat. Pig-MAP shows homology, as PK-120, with the heavy chain 2 (HC-2) of the inter-alpha-trypsin inhibitor superfamily but does not possess trypsin inhibitory activity.
| Predicate | Object |
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| rdf:type | |
| rdfs:comment |
A major acute phase protein (pig-MAP) has been isolated from the sera of pigs after turpentine injection. The protein is the pig counterpart of a recently cloned human serum protein denominated PK-120, which is a putative substrate for kallikrein [Nishimura et al., 1995 FEBS Lett. 357, 207-211]. The protein exists in other mammalian species and it is also an acute phase protein, at least in the rat. Pig-MAP shows homology, as PK-120, with the heavy chain 2 (HC-2) of the inter-alpha-trypsin inhibitor superfamily but does not possess trypsin inhibitory activity.
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| skos:exactMatch | |
| uniprot:name |
FEBS Lett.
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| uniprot:author |
Alava M.A.,
Escartin A.,
Garcia-Gil A.,
Gonzalez-Ramon N.,
Lampreave F.,
Pineiro A.,
Pineiro M.,
Sarsa J.A.
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| uniprot:date |
1995
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| uniprot:pages |
227-230
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| uniprot:title |
The major acute phase serum protein in pigs is homologous to human plasma kallikrein sensitive PK-120.
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| uniprot:volume |
371
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| dc-term:identifier |
doi:10.1016/0014-5793(95)00882-A
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