The gene for the sheep arginine vasopressin type 1a (V1a) receptor subtype was cloned from a genomic library. The deduced amino acid sequence shows characteristics of a G-protein coupled receptor and high sequence identity to human and rat V1a receptor sequences (81% and 73%, respectively). Reverse transcription-polymerase chain reaction (RT-PCR) analysis showed a tissue distribution consistent with a type V1a receptor. The genomic DNA (7.1 kb) contains a 1586 bp intron between the putative 6th and 7th transmembrane domains.
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rdfs:comment |
The gene for the sheep arginine vasopressin type 1a (V1a) receptor subtype was cloned from a genomic library. The deduced amino acid sequence shows characteristics of a G-protein coupled receptor and high sequence identity to human and rat V1a receptor sequences (81% and 73%, respectively). Reverse transcription-polymerase chain reaction (RT-PCR) analysis showed a tissue distribution consistent with a type V1a receptor. The genomic DNA (7.1 kb) contains a 1586 bp intron between the putative 6th and 7th transmembrane domains.
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skos:exactMatch | |
uniprot:name |
Biochim. Biophys. Acta
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uniprot:author |
Burrell L.M.,
Hutchins A.-M.,
Johnston C.I.,
Phillips P.A.,
Venter D.J.
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uniprot:date |
1995
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uniprot:pages |
266-270
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uniprot:title |
Molecular cloning and sequencing of the gene encoding a sheep arginine vasopressin type 1a receptor.
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uniprot:volume |
1263
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dc-term:identifier |
doi:10.1016/0167-4781(95)00125-Z
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