NF-kappa B is a transcription factor composed of the p50 and p65 subunits. Recent works identified another human gene which encodes a molecule related to the p50 subunit, termed p50B, p49 or lyt-10. Here, we isolated the cDNA clones encoding chicken p50B/p97 (Lyt-10). The deduced amino acid sequence of the precursor protein, p97, shows conservation of the overall structure, and 86% identity in the Rel homology domain (RHD) and 56% identity in the ankyrin repeat domain (ARD) to human p50B/p97. Expression of this gene is highest in the chicken spleen.
| Predicate | Object |
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| rdf:type | |
| rdfs:comment |
NF-kappa B is a transcription factor composed of the p50 and p65 subunits. Recent works identified another human gene which encodes a molecule related to the p50 subunit, termed p50B, p49 or lyt-10. Here, we isolated the cDNA clones encoding chicken p50B/p97 (Lyt-10). The deduced amino acid sequence of the precursor protein, p97, shows conservation of the overall structure, and 86% identity in the Rel homology domain (RHD) and 56% identity in the ankyrin repeat domain (ARD) to human p50B/p97. Expression of this gene is highest in the chicken spleen.
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| skos:exactMatch | |
| uniprot:name |
Gene
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| uniprot:author |
Hirota Y.,
Ikeda T.,
Onodera T.
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| uniprot:date |
1994
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| uniprot:pages |
193-196
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| uniprot:title |
Isolation of a cDNA encoding the chicken p50B/p97 (Lyt-10) transcription factor.
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| uniprot:volume |
138
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| dc-term:identifier |
doi:10.1016/0378-1119(94)90806-0
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