Bovine fetal and adult globin genes were cloned and subjected to DNA sequence analysis. Both of these genes contained insertions of Alu-type repetitive DNA within their introns. Comparison of cow and goat beta-type globin genes indicates that intragenic DNA insertions played a role in their evolution. These data support the theory that Alu-type repeats maintain genetic diversity by inhibiting gene conversion.
| Predicate | Object |
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| rdf:type | |
| rdfs:comment |
Bovine fetal and adult globin genes were cloned and subjected to DNA sequence analysis. Both of these genes contained insertions of Alu-type repetitive DNA within their introns. Comparison of cow and goat beta-type globin genes indicates that intragenic DNA insertions played a role in their evolution. These data support the theory that Alu-type repeats maintain genetic diversity by inhibiting gene conversion.
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| skos:exactMatch | |
| uniprot:name |
Nucleic Acids Res.
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| uniprot:author |
Duncan C.H.,
Schimenti J.C.
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| uniprot:date |
1984
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| uniprot:pages |
1641-1655
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| uniprot:title |
Ruminant globin gene structures suggest an evolutionary role for Alu-type repeats.
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| uniprot:volume |
12
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| dc-term:identifier |
doi:10.1093/nar/12.3.1641
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