The his4-912 mutation results from insertion of a transposable element into the 5'-non-coding region of the his4 gene of yeast. A duplication of 5 base pairs of wild-type his4 DNA flanks the inserted element. The major class of His+ revertants result from excision of most of the transposable element, leaving an inserted segment of 334 base pairs flanked by the 5-base pair repeats.
| Predicate | Object |
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| rdf:type | |
| rdfs:comment |
The his4-912 mutation results from insertion of a transposable element into the 5'-non-coding region of the his4 gene of yeast. A duplication of 5 base pairs of wild-type his4 DNA flanks the inserted element. The major class of His+ revertants result from excision of most of the transposable element, leaving an inserted segment of 334 base pairs flanked by the 5-base pair repeats.
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| skos:exactMatch | |
| uniprot:name |
Nature
|
| uniprot:author |
Farabaugh P.J.,
Fink G.R.
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| uniprot:date |
1980
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| uniprot:pages |
352-356
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| uniprot:title |
Insertion of the eukaryotic transposable element Ty1 creates a 5-base pair duplication.
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| uniprot:volume |
286
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| dc-term:identifier |
doi:10.1038/286352a0
|