Nucleic Acids Res.

A novel human leukocyte interferon cDNA clone (LeIF B) was identified in a cDNA library prepared using polyadenylated mRNA of a myeloblastoid cell line. The nucleotide sequence of LeIF B differs significantly from other published leukocyte interferon cDNA sequences. An expression plasmid was constructed which directs the synthesis in E. coli of 8 x 10(7) interferon units per liter of culture. LeIF B exhibits markedly different specificities from another bacterially synthesized human leukocyte interferon, LeIF A.

Source:http://purl.uniprot.org/citations/6164048

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A novel human leukocyte interferon cDNA clone (LeIF B) was identified in a cDNA library prepared using polyadenylated mRNA of a myeloblastoid cell line. The nucleotide sequence of LeIF B differs significantly from other published leukocyte interferon cDNA sequences. An expression plasmid was constructed which directs the synthesis in E. coli of 8 x 10(7) interferon units per liter of culture. LeIF B exhibits markedly different specificities from another bacterially synthesized human leukocyte interferon, LeIF A.
skos:exactMatch
uniprot:name
Nucleic Acids Res.
uniprot:author
Goeddel D.V., Gray P.W., Leung D., Weck P., Yelverton E.
uniprot:date
1981
uniprot:pages
731-741
uniprot:title
Bacterial synthesis of a novel human leukocyte interferon.
uniprot:volume
9
dc-term:identifier
doi:10.1093/nar/9.3.731