Complete sequencing of plasmid pOXA-48a carrying the bla(OXA-48) gene from a Klebsiella pneumoniae isolate was performed. Its backbone corresponded to that of an IncL/M-type plasmid, in which the bla(OXA-48) gene had been integrated through the acquisition of the Tn1999 composite transposon without any other antibiotic resistance gene. Molecular epidemiology using a collection of international OXA-48 producers revealed the wide diffusion of pOXA-48a or closely related plasmids.
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rdf:type | |
rdfs:comment |
Complete sequencing of plasmid pOXA-48a carrying the bla(OXA-48) gene from a Klebsiella pneumoniae isolate was performed. Its backbone corresponded to that of an IncL/M-type plasmid, in which the bla(OXA-48) gene had been integrated through the acquisition of the Tn1999 composite transposon without any other antibiotic resistance gene. Molecular epidemiology using a collection of international OXA-48 producers revealed the wide diffusion of pOXA-48a or closely related plasmids.
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skos:exactMatch | |
uniprot:name |
Antimicrob. Agents Chemother.
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uniprot:author |
Bonnin R.A.,
Nordmann P.,
Poirel L.
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uniprot:date |
2012
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uniprot:pages |
559-562
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uniprot:title |
Genetic Features of the Widespread Plasmid Coding for the Carbapenemase OXA-48.,
Genetic features of the widespread plasmid coding for the carbapenemase OXA-48.
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uniprot:volume |
56
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dc-term:identifier |
doi:10.1128/AAC.05289-11
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