Human respiratory syncytial virus (HRSV) strains were isolated from nasopharyngeal aspirates collected from 965 children between 2004 and 2005, yielding 424 positive samples. We sequenced the small hydrophobic protein (SH) gene of 117 strains and compared them with other viruses identified worldwide. Phylogenetic analysis showed a low genetic variability among the isolates but allowed us to classify the viruses into different genotypes for both groups, HRSVA and HRSVB. It is also shown that the novel BA-like genotype was well segregated from the others, indicating that the mutations are not limited to the G gene.
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|---|---|
| rdf:type | |
| rdfs:comment |
Human respiratory syncytial virus (HRSV) strains were isolated from nasopharyngeal aspirates collected from 965 children between 2004 and 2005, yielding 424 positive samples. We sequenced the small hydrophobic protein (SH) gene of 117 strains and compared them with other viruses identified worldwide. Phylogenetic analysis showed a low genetic variability among the isolates but allowed us to classify the viruses into different genotypes for both groups, HRSVA and HRSVB. It is also shown that the novel BA-like genotype was well segregated from the others, indicating that the mutations are not limited to the G gene.
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| skos:exactMatch | |
| uniprot:name |
Virus Res.
|
| uniprot:author |
Bosso P.A.,
Botosso V.F.,
Campos A.C.,
Durigon E.L.,
Filho C.G.,
Gilio A.E.,
Leal A.L.,
Leal Oliveira D.B.,
Lima H.N.,
Moraes C.T.,
Oliveira D.B.,
Pedroso Moraes C.T.,
Ramos Bosso P.A.,
Silva T.S.,
Stewien K.E.,
Vieira S.E.,
da Silva Filho C.G.,
de Almeida Campos A.C.
|
| uniprot:date |
2012
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| uniprot:pages |
82-86
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| uniprot:title |
Molecular epidemiology of the SH (small hydrophobic) gene of human respiratory syncytial virus (HRSV), over 2 consecutive years.
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| uniprot:volume |
163
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| dc-term:identifier |
doi:10.1016/j.virusres.2011.08.013
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