The first allele of a 16S rRNA methyltransferase gene, rmtD2, conferring very high resistance to all clinically available aminoglycosides, was detected in 7/1,064 enterobacteria collected in 2007. rmtD2 was located on a conjugative plasmid in a Tn2670-like element inside a structure similar to that of rmtD1 but probably having an independent assembly. rmtD2 has been found since 1996 to 1998 mainly in Enterobacter and Citrobacter isolates, suggesting a possible reservoir in these genera. This presumption deserves monitoring by continuous surveillance.
| Predicate | Object |
|---|---|
| rdf:type | |
| rdfs:comment |
The first allele of a 16S rRNA methyltransferase gene, rmtD2, conferring very high resistance to all clinically available aminoglycosides, was detected in 7/1,064 enterobacteria collected in 2007. rmtD2 was located on a conjugative plasmid in a Tn2670-like element inside a structure similar to that of rmtD1 but probably having an independent assembly. rmtD2 has been found since 1996 to 1998 mainly in Enterobacter and Citrobacter isolates, suggesting a possible reservoir in these genera. This presumption deserves monitoring by continuous surveillance.
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| skos:exactMatch | |
| uniprot:name |
Antimicrob. Agents Chemother.
|
| uniprot:author |
Andres P.,
Chung C.,
Corso A.,
Galas M.,
Low D.E.,
Lucero C.,
Melano R.G.,
Petroni A.,
Tijet N.
|
| uniprot:date |
2011
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| uniprot:group |
WHONET-Argentina Group
|
| uniprot:pages |
904-909
|
| uniprot:title |
rmtD2, a new allele of a 16S rRNA methylase gene, has been present in Enterobacteriaceae isolates from Argentina for more than a decade.
|
| uniprot:volume |
55
|
| dc-term:identifier |
doi:10.1128/AAC.00962-10
|