BACKGROUND: Haloferax volcanii is an easily culturable moderate halophile that grows on simple defined media, is readily transformable, and has a relatively stable genome. This, in combination with its biochemical and genetic tractability, has made Hfx. volcanii a key model organism, not only for the study of halophilicity, but also for archaeal biology in general. METHODOLOGY/PRINCIPAL FINDINGS: We report here the sequencing and analysis of the genome of Hfx. volcanii DS2, the type strain of this species. The genome contains a main 2.848 Mb chromosome, three smaller chromosomes pHV1, 3, 4 (85, 438, 636 kb, respectively) and the pHV2 plasmid (6.4 kb). CONCLUSIONS/SIGNIFICANCE: The completed genome sequence, presented here, provides an invaluable tool for further in vivo and in vitro studies of Hfx. volcanii.
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| rdf:type | |
| rdfs:comment |
BACKGROUND: Haloferax volcanii is an easily culturable moderate halophile that grows on simple defined media, is readily transformable, and has a relatively stable genome. This, in combination with its biochemical and genetic tractability, has made Hfx. volcanii a key model organism, not only for the study of halophilicity, but also for archaeal biology in general. METHODOLOGY/PRINCIPAL FINDINGS: We report here the sequencing and analysis of the genome of Hfx. volcanii DS2, the type strain of this species. The genome contains a main 2.848 Mb chromosome, three smaller chromosomes pHV1, 3, 4 (85, 438, 636 kb, respectively) and the pHV2 plasmid (6.4 kb). CONCLUSIONS/SIGNIFICANCE: The completed genome sequence, presented here, provides an invaluable tool for further in vivo and in vitro studies of Hfx. volcanii.
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| skos:exactMatch | |
| uniprot:name |
PLoS ONE
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| uniprot:author |
Allers T.,
Badger J.H.,
Daniels C.,
Delmas S.,
Eisen J.A.,
Haldenby S.,
Hartman A.L.,
Khouri H.,
Lowe T.M.,
Madupu R.,
Maupin-Furlow J.,
Norais C.,
Pfeiffer F.,
Pohlschroder M.,
Ren Q.,
Robinson J.
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| uniprot:date |
2010
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| uniprot:pages |
E9605
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| uniprot:title |
The complete genome sequence of Haloferax volcanii DS2, a model archaeon.
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| uniprot:volume |
5
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| dc-term:identifier |
doi:10.1371/journal.pone.0009605
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