Three distinct multiresistant loci from enterobacterial plasmids each comprised an integron and an IS26-associated sequence. Sequence comparison suggested a common ancestral structure that derived from an IS26 insertion into the 5' conserved segment of an In4-type integron and evolved through acquisition of gene cassettes and IS26-mediated recruitment of additional resistance genes of diverse origin.
| Predicate | Object |
|---|---|
| rdf:type | |
| rdfs:comment |
Three distinct multiresistant loci from enterobacterial plasmids each comprised an integron and an IS26-associated sequence. Sequence comparison suggested a common ancestral structure that derived from an IS26 insertion into the 5' conserved segment of an In4-type integron and evolved through acquisition of gene cassettes and IS26-mediated recruitment of additional resistance genes of diverse origin.
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| skos:exactMatch | |
| uniprot:name |
Antimicrob. Agents Chemother.
|
| uniprot:author |
Carattoli A.,
Miriagou V.,
Tzelepi E.,
Tzouvelekis L.S.,
Villa L.
|
| uniprot:date |
2005
|
| uniprot:pages |
3541-3543
|
| uniprot:title |
IS26-associated In4-type integrons forming multiresistance loci in enterobacterial plasmids.
|
| uniprot:volume |
49
|
| dc-term:identifier |
doi:10.1128/AAC.49.8.3541-3543.2005
|