Here we report the identification of inbred miniature swine that failed to produce human-tropic replication-competent porcine endogenous retroviruses (HTRC PERVs), using in vitro coculture assays. When HTRC PERVs were isolated from transmitting animals, all were recombinant viruses, with the receptor-binding domain of PERV-A combining with PERV-C-related sequences.
| Predicate | Object |
|---|---|
| rdf:type | |
| rdfs:comment |
Here we report the identification of inbred miniature swine that failed to produce human-tropic replication-competent porcine endogenous retroviruses (HTRC PERVs), using in vitro coculture assays. When HTRC PERVs were isolated from transmitting animals, all were recombinant viruses, with the receptor-binding domain of PERV-A combining with PERV-C-related sequences.
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| skos:exactMatch | |
| uniprot:name |
J. Virol.
|
| uniprot:author |
Andersson G.,
Ericsson T.A.,
Greenstein J.L.,
Oldmixon B.A.,
Patience C.,
Schuurman H.J.,
White-Scharf M.E.,
Wilson C.A.,
Wood J.C.
|
| uniprot:date |
2002
|
| uniprot:pages |
3045-3048
|
| uniprot:title |
Porcine endogenous retrovirus transmission characteristics of an inbred herd of miniature swine.
|
| uniprot:volume |
76
|
| dc-term:identifier |
doi:10.1128/JVI.76.6.3045-3048.2002
|