We sequenced the rhesus lymphocryptovirus (LCV) genome in order to determine its genetic similarity to Epstein-Barr virus (EBV). The rhesus LCV encodes a repertoire identical to that of EBV, with 80 open reading frames, including cellular interleukin-10, bcl-2, and colony-stimulating factor 1 receptor homologues and an equivalent set of viral glycoproteins. The highly conserved rhesus LCV gene repertoire provides a unique animal model for the study of EBV pathogenesis.
| Predicate | Object |
|---|---|
| rdf:type | |
| rdfs:comment |
We sequenced the rhesus lymphocryptovirus (LCV) genome in order to determine its genetic similarity to Epstein-Barr virus (EBV). The rhesus LCV encodes a repertoire identical to that of EBV, with 80 open reading frames, including cellular interleukin-10, bcl-2, and colony-stimulating factor 1 receptor homologues and an equivalent set of viral glycoproteins. The highly conserved rhesus LCV gene repertoire provides a unique animal model for the study of EBV pathogenesis.
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| skos:exactMatch | |
| uniprot:name |
J. Virol.
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| uniprot:author |
Cho Y.G.,
Jiang H.,
Quink C.,
Rivailler P.,
Wang F.
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| uniprot:date |
2002
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| uniprot:pages |
421-426
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| uniprot:title |
Complete nucleotide sequence of the rhesus lymphocryptovirus: genetic validation for an Epstein-Barr virus animal model.
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| uniprot:volume |
76
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| dc-term:identifier |
doi:10.1128/JVI.76.1.421-426.2002
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