The U-box is a highly conserved domain recently identified at the C terminus of yeast UFD2, an E4 ubiquitination factor. In yeast, UFD2 is the only U-box-containing protein, but there are two UFD2 homologs and several other proteins containing a U-box domain in humans. Intriguingly, a database search revealed 37 predicted proteins containing a U-box in Arabidopsis. The plant U-box (PUB) proteins form five distinct subclasses, suggesting that they play diverse roles. The ARC1 gene from Brassica, required for self-incompatibility, is currently the only PUB gene functionally characterized. Here, we discuss the characteristics and possible functions of the PUB gene family.
| Predicate | Object |
|---|---|
| rdf:type | |
| rdfs:comment |
The U-box is a highly conserved domain recently identified at the C terminus of yeast UFD2, an E4 ubiquitination factor. In yeast, UFD2 is the only U-box-containing protein, but there are two UFD2 homologs and several other proteins containing a U-box domain in humans. Intriguingly, a database search revealed 37 predicted proteins containing a U-box in Arabidopsis. The plant U-box (PUB) proteins form five distinct subclasses, suggesting that they play diverse roles. The ARC1 gene from Brassica, required for self-incompatibility, is currently the only PUB gene functionally characterized. Here, we discuss the characteristics and possible functions of the PUB gene family.
|
| skos:exactMatch | |
| uniprot:name |
Trends Plant Sci.
|
| uniprot:author |
Azevedo C.,
Santos-Rosa M.J.,
Shirasu K.
|
| uniprot:date |
2001
|
| uniprot:pages |
354-358
|
| uniprot:title |
The U-box protein family in plants.
|
| uniprot:volume |
6
|
| dc-term:identifier |
doi:10.1016/S1360-1385(01)01960-4
|