EEAC0CEA7C273DAB42E6D22A69C2FE739A51AC42ABFABC7DC5087D3D5727FF95776555D56296F9616F058AE4BAA2FEB0

In ArIB[V11L]; very highly potent against alpha-7 nAChR (IC(50)=0.54 nM). In ArIB[V11L,V16A]; very highly potent against alpha-7 nAChR (IC(50)=0.36 nM). In ArIB[V11L,V16D]; highly potent against alpha-7 nAChR (IC(50)=1.1 nM).

Source:http://purl.uniprot.org/SHA-384/EEAC0CEA7C273DAB42E6D22A69C2FE739A51AC42ABFABC7DC5087D3D5727FF95776555D56296F9616F058AE4BAA2FEB0

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Predicate	Object
rdf:type	uniprot:Mutagenesis_Annotation
rdfs:comment	In ArIB[V11L]; very highly potent against alpha-7 nAChR (IC(50)=0.54 nM). In ArIB[V11L,V16A]; very highly potent against alpha-7 nAChR (IC(50)=0.36 nM). In ArIB[V11L,V16D]; highly potent against alpha-7 nAChR (IC(50)=1.1 nM).
uniprot:range	http://purl.uniprot.org/range/22571063402705453tt30tt30
uniprot:substitution	L