ECFBA6AE8A5ED68E4F85B5707C1837D49408DD6C2FA4AD2C6EA7346F0F6D92CA121BBD16857D2C8975A960163D4E5614

May form trimers with another SMAD1 and the co-SMAD SMAD4. Interacts with PEBP2-alpha subunit, CREB-binding protein (CBP), NANOG, p300, SMURF1, SMURF2, HOXC8, USP15 and HGS. Associates with ZNF423 or ZNF521 in response to BMP2 leading to activate transcription of BMP target genes. Interacts with SKOR1 and ZCCHC12. Interacts (via MH2 domain) with LEMD3. Binding to LEMD3 results in at least a partial reduction of receptor-mediated phosphorylation (By similarity). Forms a ternary complex with PSMB4 and OAZ1 before PSMB4 is incorporated into the 20S proteasome (By similarity).

Source:http://purl.uniprot.org/SHA-384/ECFBA6AE8A5ED68E4F85B5707C1837D49408DD6C2FA4AD2C6EA7346F0F6D92CA121BBD16857D2C8975A960163D4E5614

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Statements in which the resource exists as a subject.
Predicate	Object
rdf:type	uniprot:Subunit_Annotation
rdfs:comment	May form trimers with another SMAD1 and the co-SMAD SMAD4. Interacts with PEBP2-alpha subunit, CREB-binding protein (CBP), NANOG, p300, SMURF1, SMURF2, HOXC8, USP15 and HGS. Associates with ZNF423 or ZNF521 in response to BMP2 leading to activate transcription of BMP target genes. Interacts with SKOR1 and ZCCHC12. Interacts (via MH2 domain) with LEMD3. Binding to LEMD3 results in at least a partial reduction of receptor-mediated phosphorylation (By similarity). Forms a ternary complex with PSMB4 and OAZ1 before PSMB4 is incorporated into the 20S proteasome (By similarity).