E58F6F1027D2308812B6288EC9544320B1A9667F2DFAA3430EE6B85FB20F2D17D71C46AE8ADCA952EAA07271AC09C213

The soluble form derives from the membrane form by proteolytic processing. The membrane-bound form is further proteolytically processed by SPPL2A or SPPL2B through regulated intramembrane proteolysis producing TNF intracellular domains (ICD1 and ICD2) released in the cytosol and TNF C-domain 1 and C-domain 2 secreted into the extracellular space (By similarity).

Source:http://purl.uniprot.org/SHA-384/E58F6F1027D2308812B6288EC9544320B1A9667F2DFAA3430EE6B85FB20F2D17D71C46AE8ADCA952EAA07271AC09C213

Download in:

Named Graph Language Inference

Statements in which the resource exists as a subject.
Predicate	Object
rdf:type	uniprot:PTM_Annotation
rdfs:comment	The soluble form derives from the membrane form by proteolytic processing. The membrane-bound form is further proteolytically processed by SPPL2A or SPPL2B through regulated intramembrane proteolysis producing TNF intracellular domains (ICD1 and ICD2) released in the cytosol and TNF C-domain 1 and C-domain 2 secreted into the extracellular space (By similarity).