DA097A9C4A9DED2FD853B17F72C2DA2D0F07F3AD8D89103534C1727D4A3E4C1B74107970095FC192054C16C737CD37BC

Localized in the brefeldin A-sensitive Golgi compartment, at centrosomes, in the nucleus with a somewhat speckle-like presence, membrane-associated to the endoplasmic reticulum (ER) and the plasma membrane (PM), and more diffusely in the cytoplasm. Found to concentrate in splicing factor compartments (SFCs) within the nucleus of interphase cells. The acylation-negative form may be only cytoplasmic and nuclear. Acylation seems to allow the sequestering to the intracellular membranes. Myristoylation may mediate targeting to the intracellular non-Golgi membranes and palmitoylation may mediate the targeting to the Golgi membranes. Dual acylation is required to stabilize the interaction with Golgi membranes (By similarity).

Source:http://purl.uniprot.org/SHA-384/DA097A9C4A9DED2FD853B17F72C2DA2D0F07F3AD8D89103534C1727D4A3E4C1B74107970095FC192054C16C737CD37BC

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Predicate	Object
rdf:type	uniprot:Subcellular_Location_Annotation
rdfs:comment	Localized in the brefeldin A-sensitive Golgi compartment, at centrosomes, in the nucleus with a somewhat speckle-like presence, membrane-associated to the endoplasmic reticulum (ER) and the plasma membrane (PM), and more diffusely in the cytoplasm. Found to concentrate in splicing factor compartments (SFCs) within the nucleus of interphase cells. The acylation-negative form may be only cytoplasmic and nuclear. Acylation seems to allow the sequestering to the intracellular membranes. Myristoylation may mediate targeting to the intracellular non-Golgi membranes and palmitoylation may mediate the targeting to the Golgi membranes. Dual acylation is required to stabilize the interaction with Golgi membranes (By similarity).
uniprot:locatedIn	http://purl.uniprot.org/SHA-384/82DF273C49D4740824D076CE0B588A3D85A9B9EC9220E344E55FCBE..., http://purl.uniprot.org/SHA-384/98A12FE956C7E72D2CB2C460BAF8B35748D1BD37B17E50F6CF3416F..., http://purl.uniprot.org/SHA-384/BE34728959E31634C5984A46812EE748C7B9A652045F3F2DE517C2E..., http://purl.uniprot.org/SHA-384/0AA8174C15D94E5D12BD86DE96585DC64E1500ECFD4AF77D4A132C2..., http://purl.uniprot.org/SHA-384/2A01D3A4DB05A3A87689B5FCEF253BFD5023D0E87C69ADBBB3BCB52..., http://purl.uniprot.org/SHA-384/D0FA4A97625BA9A30F2A815936CCF32C42EB283C1AE0D81042DC2BB...