D3B8BA228AB5C317748E8884552EEBAA14BD7ED7A59F9149C20FD4CF431C667EAA17A6CDB90ABFFF4067D892CA1E89A0

Immediate-early gene. Plays an important role in embryonic development as well as in cellular growth and proliferation; its long-term silencing affects cell survival and cell cycle distribution as well as decreases CDK1 activity correlated with reduced phosphorylation of CDK1. Plays a role as a positive regulator of the sonic hedgehog pathway, acting downstream of PTCH1.

Source:http://purl.uniprot.org/SHA-384/D3B8BA228AB5C317748E8884552EEBAA14BD7ED7A59F9149C20FD4CF431C667EAA17A6CDB90ABFFF4067D892CA1E89A0

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Predicate	Object
rdf:type	uniprot:Function_Annotation
rdfs:comment	Immediate-early gene. Plays an important role in embryonic development as well as in cellular growth and proliferation; its long-term silencing affects cell survival and cell cycle distribution as well as decreases CDK1 activity correlated with reduced phosphorylation of CDK1. Plays a role as a positive regulator of the sonic hedgehog pathway, acting downstream of PTCH1.