D38DFD00396B24901AEEC0C7C1656F1C674CA6A925C52DBF4F7CB95F4EA94A7CC40ABE5010CEDD2DA0D26D92730DA444

Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron (By similarity).

Source:http://purl.uniprot.org/SHA-384/D38DFD00396B24901AEEC0C7C1656F1C674CA6A925C52DBF4F7CB95F4EA94A7CC40ABE5010CEDD2DA0D26D92730DA444

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Predicate	Object
rdf:type	uniprot:Function_Annotation
rdfs:comment	Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron (By similarity).