CAC872E68CA39CEAD88F620866A8ABBCC7F67B0E6F3A8C74EDE4940C4E2BB9AC87833E1CBD99768FC4D7C32D86207BDF

Involved in virus clathrin-mediated internalization through the binding to host integrin heterodimer alphaV-beta5 (ITGAV-ITGB5). In primary receptor (CXADR)-negative cells, also mediates virus attachment to host cell (By similarity). Binding to integrins ITGAV-ITGB5 also seems to be linked to macropinocytosis uptake of the virus.

Source:http://purl.uniprot.org/SHA-384/CAC872E68CA39CEAD88F620866A8ABBCC7F67B0E6F3A8C74EDE4940C4E2BB9AC87833E1CBD99768FC4D7C32D86207BDF

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Predicate	Object
rdf:type	uniprot:Function_Annotation
rdfs:comment	Involved in virus clathrin-mediated internalization through the binding to host integrin heterodimer alphaV-beta5 (ITGAV-ITGB5). In primary receptor (CXADR)-negative cells, also mediates virus attachment to host cell (By similarity). Binding to integrins ITGAV-ITGB5 also seems to be linked to macropinocytosis uptake of the virus.