The common region of ST and LT proteins comprises the J domain. This domain is essential for multiple viral activities, including virion assembly, viral DNA replication, transformation and transcriptional activation. This domain is also required for cyclin A-transactivating activity of ST (By similarity).
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The common region of ST and LT proteins comprises the J domain. This domain is essential for multiple viral activities, including virion assembly, viral DNA replication, transformation and transcriptional activation. This domain is also required for cyclin A-transactivating activity of ST (By similarity).
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