B45D3F0A87BEC796C33F29BB19E0D10937437CC90BE951A5DD5AD8D98D27A3979CBC5F16CBE02BC72F354B44DA98336F

Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling (By similarity).

Source:http://purl.uniprot.org/SHA-384/B45D3F0A87BEC796C33F29BB19E0D10937437CC90BE951A5DD5AD8D98D27A3979CBC5F16CBE02BC72F354B44DA98336F

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rdf:type	uniprot:Function_Annotation
rdfs:comment	Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling (By similarity).