A6D4971D0EE9021DC36C9F1C32B19B8796059EC5660FFDC6FAD747CC64FD0F41E0F9B5A794190B9AD623013236C3ACA1

Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells (By similarity). Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.

Source:http://purl.uniprot.org/SHA-384/A6D4971D0EE9021DC36C9F1C32B19B8796059EC5660FFDC6FAD747CC64FD0F41E0F9B5A794190B9AD623013236C3ACA1

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Predicate	Object
rdf:type	uniprot:Function_Annotation
rdfs:comment	Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells (By similarity). Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.